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Good Morning. I don't know exactly where you're starting from, and if you want more of a family retreat or a more romantic retreat, or if you might have allready been here, but one idea is to investigate the Ouachita [pronounced: Wash-ee-taw] Mountains area in Arkansas and Oklahoma. There are a wide range of types of accomdations in the region from romantic bed and breakfast inns to rustic mountain cabins.
More later.
[Photo above from Okiefromokla on Wikipedia shows Talimena Scenic Drive in Oklahoma. photo from Wikipedia]